Goal of treatment of chronic hepatitis C

The goal of treatment is cure, or SVR, defined as undetectable plasma HCV RNA at least 12 weeks after treatment has ceased. SVR is associated with multiple clinical benefits, including improvement in quality of life, loss of infectivity, regression of liver fibrosis and cirrhosis, a reduction in the risk of liver failure and HCC, and a reduction in the risk of liver-related and all-cause mortality.