Regimens for people with chronic genotype 1 HCV infection who are treatment-naive

There are six IFN-free DAA regimens that are available for PBS prescription for the treatment of Gt 1 HCV in people who are treatment-naive:

  1. sofosbuvir + velpatasvir
  2. glecaprevir + pibrentasvir
  3. elbasvir + grazoprevir
  4. sofosbuvir + ledipasvir
  5. sofosbuvir + daclatasvir ± ribavirin
  6. paritaprevir (ritonavir-boosted) + ombitasvir + dasabuvir ± ribavirin

These six well tolerated regimens have efficacy ≥ 95% across all patient groups.